Using PCOMM to check operation of devices connected to serial server:
In this case you can also see the serial server in the Advantech Utility and may assume it is connected:
However, when you ping the server you get no response. This is because the server gets discovered via the other port and the Auto-IP address from windows 169.254....
In this case you need to either physically swap the RJ45 connector to the other port on the serial server, or change 22.214.171.124 to 192.168.42.10 after changing 192.168.42.10 to .11.